BDBM505 3-[2H-1,3-benzodioxol-5-yl(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]-4-hydroxy-2H-chromen-2-one::CHEMBL64213::Cancer Chemotherapy National Service Center (CCNSC) compound 373937::NSC 373937

SMILES Oc1c(C(c2ccc3OCOc3c2)c2c(O)c3ccccc3oc2=O)c(=O)oc2ccccc12

InChI Key InChIKey=RRHGSCFLDXVUNI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 505   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM505(3-[2H-1,3-benzodioxol-5-yl(4-hydroxy-2-oxo-2H-chro...)
Affinity DataIC50:  3.00E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM505(3-[2H-1,3-benzodioxol-5-yl(4-hydroxy-2-oxo-2H-chro...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM505(3-[2H-1,3-benzodioxol-5-yl(4-hydroxy-2-oxo-2H-chro...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM505(3-[2H-1,3-benzodioxol-5-yl(4-hydroxy-2-oxo-2H-chro...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed