BDBM50500748 CHEMBL3753156

SMILES I.COc1ccc(CN(Cc2ccccc2)C2=NCC(CI)S2)cc1

InChI Key InChIKey=RXXQDXOURVMKKU-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50500748   

TargetLiver carboxylesterase(Sus scrofa)
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50500748(CHEMBL3753156)
Affinity DataKi:  7.81E+3nMAssay Description:Noncompetitive inhibition of porcine liver carboxylesterase using 4-nitrophenol acetate as substrate assessed as steady state inhibition constant pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase(Sus scrofa)
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50500748(CHEMBL3753156)
Affinity DataIC50:  4.66E+3nMAssay Description:Inhibition of porcine liver carboxylesterase using 4-nitrophenol acetate as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Institute Of Physiologically Active Compounds Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50500748(CHEMBL3753156)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed