BDBM50502491 CHEMBL4443354::US11834430, Compound 41

SMILES C[C@H](COc1cccc(c1)-n1ccnc1C1CC1)Oc1ccc(cc1F)C#N

InChI Key InChIKey=CNLDJPRZJYYHID-OAHLLOKOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502491   

TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM50502491(CHEMBL4443354 | US11834430, Compound 41)
Affinity DataIC50:  0.00200nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM50502491(CHEMBL4443354 | US11834430, Compound 41)
Affinity DataIC50:  0.00200nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed