BDBM50502491 CHEMBL4443354::US11834430, Compound 41
SMILES C[C@H](COc1cccc(c1)-n1ccnc1C1CC1)Oc1ccc(cc1F)C#N
InChI Key InChIKey=CNLDJPRZJYYHID-OAHLLOKOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50502491
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 0.00200nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 0.00200nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair