BDBM50503861 CHEMBL4565268

SMILES Brc1ccc2C(=O)NCCc2c1

InChI Key InChIKey=FQPKKECSRKYXIZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50503861   

TargetProtein mono-ADP-ribosyltransferase PARP11(Homo sapiens)
Oregon Health And Science University

Curated by ChEMBL
LigandPNGBDBM50503861(CHEMBL4565268)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Oregon Health And Science University

Curated by ChEMBL
LigandPNGBDBM50503861(CHEMBL4565268)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Oregon Health And Science University

Curated by ChEMBL
LigandPNGBDBM50503861(CHEMBL4565268)
Affinity DataIC50:  1.71E+4nMAssay Description:Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Homo sapiens)
Oregon Health And Science University

Curated by ChEMBL
LigandPNGBDBM50503861(CHEMBL4565268)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed