BDBM50503865 CHEMBL4544104
SMILES Cc1c2CCNC(=O)c2ccc1-c1ccccc1
InChI Key InChIKey=ZZFIVVAQPLYJOE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50503865
TargetProtein mono-ADP-ribosyltransferase PARP11(Homo sapiens)
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP11(Homo sapiens)
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Oregon Health And Science University
Curated by ChEMBL
Oregon Health And Science University
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...More data for this Ligand-Target Pair