BDBM50503894 CHEMBL4591218

SMILES CCOc1nc(CC)c(CNC(=O)[C@@H](CS)CC(C)C)n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key InChIKey=PAQFIXCBKVQCFX-JOCHJYFZSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503894   

TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Theravance Biopharma Us

Curated by ChEMBL
LigandPNGBDBM50503894(CHEMBL4591218)
Affinity DataKi:  1.30nMAssay Description:Displacement of Europium-labeled angiotensin-2 from human AT1 receptor expressed in CHOK1 cell membranes after 120 mins by DELFIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Theravance Biopharma Us

Curated by ChEMBL
LigandPNGBDBM50503894(CHEMBL4591218)
Affinity DataIC50:  32nMAssay Description:Inhibition of NEP (unknown origin) preincubated for 10 mins followed by fluorogenic substrate addition and measured after 20 mins by fluorescence ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed