BDBM50508727 (+)-Aromoline::CHEMBL508781

SMILES [H][C@@]12Cc3ccc(O)c(Oc4ccc(C[C@]5([H])N(C)CCc6cc(OC)c(O)c(Oc7cc1c(CCN2C)cc7OC)c56)cc4)c3

InChI Key InChIKey=LFFQVHXIFJLJSP-IZLXSDGUSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50508727   

TargetCholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50508727((+)-Aromoline | CHEMBL508781)
Affinity DataKi:  6.41E+3nMAssay Description:Mixed-type inhibition of human BuChE assessed as enzyme-inhibitor complex using butyrylthiocholine iodide as substrate by Lineweaver-Burk plot analys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50508727((+)-Aromoline | CHEMBL508781)
Affinity DataKi:  3.97E+4nMAssay Description:Mixed-type inhibition of human BuChE assessed as enzyme-substrate-inhibitor complex using butyrylthiocholine iodide as substrate by Lineweaver-Burk p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50508727((+)-Aromoline | CHEMBL508781)
Affinity DataIC50:  800nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate measured for 1 min by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50508727((+)-Aromoline | CHEMBL508781)
Affinity DataIC50:  1.89E+5nMAssay Description:Inhibition of POP (unknown origin) using (Z)-Gly-Pro-p-nitroanilide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50508727((+)-Aromoline | CHEMBL508781)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured for 1 min by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed