BDBM50508759 CHEMBL4444592

SMILES CN1CC(n2c(Cc3cnc(C)cn3)nc3cnc4ccc(cc4c23)C#N)C(F)(F)C1

InChI Key InChIKey=OFPQWONUEIBKMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508759   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508759(CHEMBL4444592)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of GST-tagged LRRK2 G2019S mutant (unknown origin) expressed in baculovirus expression system using fluorescein-labeled LRRKtide as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508759(CHEMBL4444592)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of recombinant wild-type GST-tagged LRRK2 (unknown origin) expressed in baculovirus expression system using fluorescein-labeled LRRKtide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed