BDBM50509082 CHEMBL4576393

SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC(C)(C)CNc1nccc(n1)N1CCN(CC1)C(N)=N

InChI Key InChIKey=DVONFQOOYIDACY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50509082   

TargetHistamine H4 receptor(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509082(CHEMBL4576393)
Affinity DataKi:  617nMAssay Description:Displacement of 10 nM [3H]-histamine from human H4R expressed in Sf9 cell membranes co-expressing Gia2 and beta1gamma2 by competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509082(CHEMBL4576393)
Affinity DataKi: <1.00E+3nMAssay Description:Displacement of 5 nM [3H-pyrilamine from human H1R expressed in Sf9 cell membranes co-expressing RGS4 by competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509082(CHEMBL4576393)
Affinity DataKi:  6.03E+3nMAssay Description:Displacement of 3 nM [3H]Nalpha-methylhistamine from human H3R expressed in Sf9 cell membranes co-expressing Gia2 and beta1gamma2 by competition bind...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509082(CHEMBL4576393)
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of 20 nM [3H]UR-DE257 from human H2R expressed in Sf9 cell membranes co-expressing GsalphaS by competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed