BDBM50509703 CHEMBL4435058

SMILES Clc1ccc(NC(=S)NNc2c3CCCCc3nc3ccccc23)cc1

InChI Key InChIKey=HSUWPQYTIZQCMM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50509703   

TargetAcetylcholinesterase(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509703(CHEMBL4435058)
Affinity DataIC50:  786nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate pre-incubated for 20 mins before substrate addition and measured for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509703(CHEMBL4435058)
Affinity DataIC50:  3.83E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 10 mins by spectrophotometry based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509703(CHEMBL4435058)
Affinity DataIC50:  328nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate pre-incubated for 20 mins before substrate addition and measured for 180 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed