BDBM50509710 CHEMBL4447258

SMILES Cl.[O-][N+](=O)c1cccc(c1)-n1cc(COc2ccc(\C=N\Nc3c4CCCCc4nc4ccccc34)cc2)nn1

InChI Key InChIKey=QITWJESFLCUKMK-KZALGFBESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50509710   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509710(CHEMBL4447258)
Affinity DataIC50:  66nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 10 mins by spectrophotometry based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509710(CHEMBL4447258)
Affinity DataIC50:  48nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate pre-incubated for 20 mins before substrate addition and measured for 180 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509710(CHEMBL4447258)
Affinity DataIC50:  1.46E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate pre-incubated for 20 mins before substrate addition and measured for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed