BDBM50510184 CHEMBL4440880
SMILES CN1CCOc2c1cnn1c(nnc21)-c1ccc2cccc(NCC3CCNCC3)c2c1
InChI Key InChIKey=ZQSFRZOCLWDZFX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50510184
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of His tagged human recombinant PIM1 using PIM tide (ARKRRRHPSGPPTA) as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataEC50: 865nMAssay Description:Inhibition of PIM1 in human NCI-H1299 cells assessed as reduction in BAD phosphorylation at Ser-112 residue incubated for 4 hrs by ELISAMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of N-terminal 6-His tagged human recombinant PIM3 using PIM tide (ARKRRRHPSGPPTA) as substrate incubated for 1 hr by fluorescence based as...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Spanish National Cancer Research Centre (Cnio)
Curated by ChEMBL
Affinity DataIC50: 4.87E+3nMAssay Description:Inhibition of His tagged human recombinant PIM2 using PIM tide (ARKRRRHPSGPPTA) as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair