BDBM50510307 CHEMBL4465076
SMILES COc1ccc(F)cc1C(C)Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1
InChI Key InChIKey=KWESEOYSTBXZIE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50510307
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
East China University Of Science & Technology
Curated by ChEMBL
East China University Of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant N-terminal hexahistidine tagged JAK2 JH1 catalytic domain (835 to 1132 residues) expressed in baculovirus infected Sf...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
East China University Of Science & Technology
Curated by ChEMBL
East China University Of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human recombinant C-terminal hexahistidine tagged JAK3 JH1 catalytic domain (811 to 1124 residues) expressed in baculovirus infected Sf...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
East China University Of Science & Technology
Curated by ChEMBL
East China University Of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 794nMAssay Description:Inhibition of TYK2 (unknown origin) using peptide as substrate preincubated for 10 mins followed by substrate addition by mobility shift assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
East China University Of Science & Technology
Curated by ChEMBL
East China University Of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant N-terminal hexahistidine tagged JAK1 JH1 catalytic domain (854 to 1154 residues) expressed in baculovirus infected Sf...More data for this Ligand-Target Pair