BDBM50513374 CHEMBL4466130
SMILES O=c1[nH]cnc2c(nccc12)-n1cc(CCN2CCC(CC2)c2ccc(CCN3CCOCC3)cc2)cn1
InChI Key InChIKey=NLYFSJWBMSCWSU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50513374
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of KDM5C (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of N-terminal His-tagged recombinant human KDM4A (1 to 359 residues) expressed in Escherichia coli assessed as decrease in demethylation o...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of KDM5B (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair