BDBM50513882 CHEMBL4523007
SMILES COc1n[nH]c2ncc(cc12)-c1cn(nn1)-c1c(F)ccc(NC(=O)c2cccc(Cl)c2)c1F
InChI Key InChIKey=BGASXKCQPAUFOH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50513882
TargetMitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full-length ZAK expressed in baculovirus infected Sf9 insect cells using MBP as substrate after...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human B-RAF V600E mutant using Ser/Thr3 as substrate after 1 hr by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair