BDBM50514586 CHEMBL4578747

SMILES [H][C@]1(O[C@@H]2[C@@H](CO)O[C@@H](OC)[C@@H]2OP(O)(O)=O)[C@H](O)[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1O

InChI Key InChIKey=QGTUTCRQEDHUBO-WLKUGORSSA-N

Data  2 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50514586   

TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50514586(CHEMBL4578747)
Affinity DataEC50:  12nMAssay Description:Agonist activity at rat IP3R1 expressed in DT40 cells assessed as increase in calcium release by Mag-fluo4 dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50514586(CHEMBL4578747)
Affinity DataEC50:  27nMAssay Description:Agonist activity at rat IP3R1 expressed in human HEK cells assessed as increase in calcium release by Mag-fluo4 dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50514586(CHEMBL4578747)
Affinity DataEC50:  12nMAssay Description:Agonist activity at rat IP3R1 expressed in DT40 cells assessed as increase in calcium release by Mag-fluo4 dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50514586(CHEMBL4578747)
Affinity DataKd:  1.40nMAssay Description:Displacement of [3H]IP3 from rat IP3R1 expressed in human HEK cells assessed as dissociation constant by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50514586(CHEMBL4578747)
Affinity DataEC50:  27nMAssay Description:Agonist activity at rat IP3R1 expressed in human HEK cells assessed as increase in calcium release by Mag-fluo4 dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50514586(CHEMBL4578747)
Affinity DataKd:  1.40nMAssay Description:Displacement of [3H]IP3 from rat IP3R1 expressed in human HEK cells assessed as dissociation constant by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed