BDBM50514587 CHEMBL4483666

SMILES [H][C@]1(O[C@@H]2[C@@H](CO)O[C@@H](OC)[C@@H]2OP(O)(O)=O)O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1O

InChI Key InChIKey=ZFGMCVXTUYJQKW-GPXGRWIWSA-N

Data  2 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50514587   

TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50514587(CHEMBL4483666)
Affinity DataEC50:  52nMAssay Description:Agonist activity at rat IP3R1 expressed in human HEK cells assessed as increase in calcium release by Mag-fluo4 dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50514587(CHEMBL4483666)
Affinity DataKd:  3.20nMAssay Description:Displacement of [3H]IP3 from rat IP3R1 expressed in human HEK cells assessed as dissociation constant by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50514587(CHEMBL4483666)
Affinity DataKd:  3.20nMAssay Description:Displacement of [3H]IP3 from rat IP3R1 expressed in human HEK cells assessed as dissociation constant by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50514587(CHEMBL4483666)
Affinity DataEC50:  89nMAssay Description:Agonist activity at rat IP3R1 expressed in DT40 cells assessed as increase in calcium release by Mag-fluo4 dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50514587(CHEMBL4483666)
Affinity DataEC50:  52nMAssay Description:Agonist activity at rat IP3R1 expressed in human HEK cells assessed as increase in calcium release by Mag-fluo4 dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50514587(CHEMBL4483666)
Affinity DataEC50:  88nMAssay Description:Agonist activity at rat IP3R1 expressed in DT40 cells assessed as increase in calcium release by Mag-fluo4 dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed