BDBM50516083 CHEMBL4470490

SMILES [H][C@@]12C[C@@]([H])(OC[C@H]1O)c1cc(CNC(=O)NCC(=O)N3CCC[C@@H]3c3ccccc3SC)ccc1N2

InChI Key InChIKey=BICVGZIZTMOLHN-JKYAZJQKSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516083   

TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50516083(CHEMBL4470490)
Affinity DataIC50:  60nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50516083(CHEMBL4470490)
Affinity DataIC50:  4nMAssay Description:Inhibition of CypD (unknown origin) PPIase activity using N-Suc-AAPF-p-nitroanilide as substrate preincubated with enzyme for 10 mins followed by chy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed