BDBM50516096 CHEMBL4540033

SMILES CSc1ccccc1[C@H]1CCCN1C(=O)CNC(=O)NCc1ccc2NCCCc2c1

InChI Key InChIKey=AWMQVWTUQIZVPZ-OAQYLSRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516096   

TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50516096(CHEMBL4540033)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of CypD (unknown origin) PPIase activity using N-Suc-AAPF-p-nitroanilide as substrate preincubated with enzyme for 10 mins followed by chy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50516096(CHEMBL4540033)
Affinity DataIC50:  3.50E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed