BDBM50516198 CHEMBL4584367
SMILES NS(=O)(=O)Oc1ccc(cc1)-c1ccc(s1)C(=O)c1cc(F)c(F)c(O)c1F
InChI Key InChIKey=VEOHVGGIOZDGJG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50516198
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
TargetEstradiol 17-beta-dehydrogenase 2(Mus musculus)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair