BDBM50516203 CHEMBL4517151
SMILES CN(Cc1nc(no1)C1CCN(Cc2ccc(C)cc2)CC1)c1ncc(cn1)C(=O)NO
InChI Key InChIKey=DSDPQMCYEOZWTA-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50516203
TargetHistone deacetylase 11(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human HDAC11 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluore...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected in Sf9 cells using Ac-peptide-AMC as substr...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 473nMAssay Description:Inhibition of recombinant full length human HDAC4 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC5 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate...More data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 441nMAssay Description:Inhibition of recombinant C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC a...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 102nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant full length HDAC1 (unknown origin) using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant full length HDAC6 (unknown origin) using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 392nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr...More data for this Ligand-Target Pair