BDBM50516570 CHEMBL4551865::US10899738, Cpd. No 48

SMILES CC(C)N1Cc2ccccc2C(C1)(C1CCCC1)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1

InChI Key InChIKey=JHWOZNHPOMQEEW-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50516570   

TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50516570(CHEMBL4551865 | US10899738, Cpd. No 48)
Affinity DataKi:  1.40nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50516570(CHEMBL4551865 | US10899738, Cpd. No 48)
Affinity DataIC50:  7nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50516570(CHEMBL4551865 | US10899738, Cpd. No 48)
Affinity DataIC50:  7nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed