BDBM50518023 CHEMBL4513533::US10751335, Example 14
SMILES Fc1cc(Cl)ccc1CN1CCC(CC1)n1c2cc(Cl)c(Cl)cc2[nH]c1=O
InChI Key InChIKey=KYQGLUNXSLQWEB-UHFFFAOYSA-N
Data 6 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50518023
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed in human U2OS cells co-transfected with beta-arrestin-2 assessed as increase in beta-arrestin-...More data for this Ligand-Target Pair
Affinity DataEC50: 179nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membranes after 1 hr by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Inhibition of human mu-opioid receptor assessed as increase in beta arrestin 2 recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 112nMAssay Description:he CisBio cAMP cell based assay kit that uses HTRF technology was utilized to assess MOR-mediated inhibition of cAMP. Assays were performed according...More data for this Ligand-Target Pair
Affinity DataEC50: 501nMAssay Description:Inhibition of human mu-opioid receptor assessed as reduction in intracellular cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 116nMAssay Description:A standard [35S]GTPγS binding assay in membranes prepared from CHO cells expressing the human MOR was performed in a concentration response mann...More data for this Ligand-Target Pair