BDBM50519024 CHEMBL4521112

SMILES CCc1sc2ncnc(N[C@H](C)C(O)=O)c2c1-c1cccc(O)c1

InChI Key InChIKey=ZVAJPNVZGQNWQE-SECBINFHSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519024   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50519024(CHEMBL4521112)
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of N-terminal fluorescein labelled Puma-BH3 peptide from human N-terminal thrombin cleavage site-fused/His6-tagged Bcl-2 expressed in Es...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50519024(CHEMBL4521112)
Affinity DataKi:  4.50E+4nMAssay Description:Displacement of N-terminal fluorescein labelled Puma-BH3 peptide from TEV-fused His-tagged human Mcl-1 expressed in Escherichia coliBL21(DE3) pLysS c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed