BDBM50519948 CHEMBL1700161

SMILES Fc1ccc(F)c(c1)S(=O)(=O)NC(=N)NCCc1c[nH]c2ccccc12

InChI Key InChIKey=KLIVXGVUVONPGE-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50519948   

TargetEndoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519948(CHEMBL1700161)
Affinity DataKi:  5.17E+4nMAssay Description:Competitive inhibition of recombinant human C-terminal His6-tagged ERAP1 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using varying le...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519948(CHEMBL1700161)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged ERAP1 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using L-AMC as substrate mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Mus musculus)
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519948(CHEMBL1700161)
Affinity DataIC50: <1.00E+6nMAssay Description:Inhibition of recombinant mouse C-terminal His6-tagged IRAP expressed in baculovirus infected BTA-TN-5B1-4 insect cells using L-AMC as substrate meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
Kansas University Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50519948(CHEMBL1700161)
Affinity DataIC50: <1.00E+6nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged ERAP2 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using R-AMC as substrate mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed