BDBM50525965 CHEMBL4519897

SMILES Oc1cc(ccc1Cl)C(=O)c1ccc(s1)-c1cccc(NS(=O)(=O)c2ccccc2)c1

InChI Key InChIKey=PJWQHMPSYVIIQW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50525965   

TargetEstradiol 17-beta-dehydrogenase 2(Mus musculus)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525965(CHEMBL4519897)
Affinity DataIC50:  304nMAssay Description:Inhibition of mouse liver homogenate 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525965(CHEMBL4519897)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50525965(CHEMBL4519897)
Affinity DataIC50:  14nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed