BDBM50526251 CHEMBL4546897
SMILES CC(C)(C)c1ccc(CN(C(=O)CN(Cc2ccccc2C(F)(F)F)S(=O)(=O)c2ccc(F)cc2)c2ccc(cc2)C(=O)NO)cc1
InChI Key InChIKey=PPCNXZVBGIANOM-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50526251
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human HDAC6 expressed in SF9 baculoviral system using FAM-labeled acetylated peptide as substrate by EMSAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human HDAC3 expressed in SF9 baculoviral system using FAM-labeled acetylated peptide as substrate by EMSAMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of Toronto Mississauga
Curated by ChEMBL
University Of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 253nMAssay Description:Inhibition of recombinant human HDAC11 expressed in SF9 baculoviral system using FAM-labeled acetylated peptide as substrate by EMSAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human HDAC8 expressed in SF9 baculoviral system using FAM-labeled acetylated peptide as substrate by EMSAMore data for this Ligand-Target Pair