BDBM50527962 CHEMBL4442292
SMILES OC(=O)CCCCCNn1nnc2ccccc12
InChI Key InChIKey=ORPGHKGCVVGSIW-UHFFFAOYSA-N
Data 28 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 28 hits for monomerid = 50527962
Affinity DataIC50: 3.80E+5nMAssay Description:Inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using Luc-BE as substrate after 10 mins in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 2.28E+5nMAssay Description:Inhibition of CYP1A2 in human pooled liver microsomes using phenacetin as substrate preincubated with NADPH for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataIC50: 9.54E+5nMAssay Description:Inhibition of CYP2C8 in human pooled liver microsomes using amodiaquine as substrate preincubated with NADPH for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.31E+6nMAssay Description:Inhibition of CYP2C8 in human pooled liver microsomes using amodiaquine as substrate after 10 mins by UPLC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.85E+6nMAssay Description:Inhibition of CYP2D6 in human pooled liver microsomes using dextromethorphan as substrate after 10 mins by UPLC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+6nMAssay Description:Inhibition of CYP3A4/5 in human pooled liver microsomes using midazolam as substrate after 10 mins by UPLC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.58E+5nMAssay Description:Inhibition of CYP2B6 in human pooled liver microsomes using bupropion as substrate preincubated with NADPH for 30 mins followed by substrate addition...More data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+6nMAssay Description:Inhibition of CYP2D6 in human pooled liver microsomes using dextromethorphan as substrate preincubated with NADPH for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incub...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+6nMAssay Description:Inhibition of recombinant human CYP4A11 expressed in baculovirus infected insect cells using Luc-4A as substrate after 10 mins in presence of NADPH b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+6nMAssay Description:Inhibition of recombinant human CYP4F2 expressed in baculovirus infected insect cells using Luc-4F2/3 as substrate after 10 mins in presence of NADPH...More data for this Ligand-Target Pair
Affinity DataIC50: 1.52E+6nMAssay Description:Inhibition of recombinant human CYP4F3B expressed in baculovirus infected insect cells using Luc-4F2/3 as substrate after 10 mins in presence of NADP...More data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+6nMAssay Description:Inhibition of recombinant human CYP4F12 expressed in baculovirus infected insect cells using Luc-BE as substrate after 10 mins in presence of NADPH b...More data for this Ligand-Target Pair
Affinity DataIC50: 6.47E+5nMAssay Description:Inhibition of recombinant human CYP4F2 expressed in baculovirus infected insect cells using Luc-4F2/3 as substrate preincubated with NADPH for 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+6nMAssay Description:Inhibition of recombinant human CYP4F3A expressed in baculovirus infected insect cells using Luc-4F2/3 as substrate preincubated with NADPH for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 7.78E+5nMAssay Description:Inhibition of recombinant human CYP4F12 expressed in baculovirus infected insect cells using Luc-BE as substrate preincubated with NADPH for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.33E+5nMAssay Description:Inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using Luc-BE as substrate preincubated with NAD...More data for this Ligand-Target Pair
Affinity DataIC50: 1.24E+6nMAssay Description:Inhibition of recombinant human CYP4F3A expressed in baculovirus infected insect cells using Luc-4F2/3 as substrate after 10 mins in presence of NADP...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+6nMAssay Description:Inhibition of CYP2C9 in human pooled liver microsomes using tolbutamide as substrate after 10 mins by UPLC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.94E+6nMAssay Description:Inhibition of CYP2C9 in human pooled liver microsomes using tolbutamide as substrate preincubated with NADPH for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
Affinity DataIC50: 7.66E+5nMAssay Description:Inhibition of CYP3A4/5 in human pooled liver microsomes using midazolam as substrate preincubated with NADPH for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.69E+6nMAssay Description:Inhibition of recombinant human CYP4F3B expressed in baculovirus infected insect cells using Luc-4F2/3 as substrate preincubated with NADPH for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.79E+6nMAssay Description:Inhibition of CYP1A2 in human pooled liver microsomes using phenacetin as substrate after 10 mins by UPLC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+6nMAssay Description:Inhibition of CYP2C19 in human pooled liver microsomes using (S)-mephenytoin as substrate after 10 mins by UPLC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+6nMAssay Description:Inhibition of CYP2C19 in human pooled liver microsomes using (S)-mephenytoin as substrate preincubated with NADPH for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate prein...More data for this Ligand-Target Pair
Affinity DataIC50: 4.55E+5nMAssay Description:Inhibition of recombinant human CYP4A11 expressed in baculovirus infected insect cells using Luc-4A as substrate preincubated with NADPH for 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.23E+5nMAssay Description:Inhibition of CYP2B6 in human pooled liver microsomes using bupropion as substrate after 10 mins by UPLC-MS/MS analysisMore data for this Ligand-Target Pair