BDBM50529862 CHEMBL4470288

SMILES COc1cc2CCN(Cc3ccc(cc3)-c3ccc(cc3)N(S(=O)(=O)c3ccccc3)S(=O)(=O)c3ccccc3)Cc2cc1OC

InChI Key InChIKey=HPMYXWRALVVIDV-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529862   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50529862(CHEMBL4470288)
Affinity DataEC50:  15nMAssay Description:Inhibition of MDR1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation after 30 mins by calcein-AM dye based flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50529862(CHEMBL4470288)
Affinity DataEC50:  15nMAssay Description:Inhibition of MDR1 (unknown origin) expressed in MDCK cells assessed as increase in calcein-AM accumulation after 30 mins by calcein-AM dye based flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed