BDBM50532706 CHEMBL4547419

SMILES COc1cc2CCN(Cc3ccc(cc3)-c3ccc(OCCCOc4nonc4[S+]([O-])c4ccccc4)cc3)Cc2cc1OC

InChI Key InChIKey=NQYXUEQNOKDVCE-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50532706   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532706(CHEMBL4547419)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of BCRP (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532706(CHEMBL4547419)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of MDR1 (unknown origin) expressed in MDCK cells assessed as decrease in calcein-AM transport after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532706(CHEMBL4547419)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of BCRP (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50532706(CHEMBL4547419)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of MDR1 (unknown origin) expressed in MDCK cells assessed as decrease in calcein-AM transport after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed