BDBM50533756 CHEMBL4578085

SMILES Cc1nocc1[C@@H]1C[C@](C)(N=C(N)S1)c1ccc(F)cc1F

InChI Key InChIKey=JPVJYQYPHVNRRF-ZFWWWQNUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50533756   

TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50533756(CHEMBL4578085)
Affinity DataIC50:  300nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed