BDBM50535742 CHEMBL4592659

SMILES CN(C)c1ccc2n(C)c(=O)n(-c3ccc(C[C@H](NC(=O)c4c(Cl)cccc4Cl)C(O)=O)cc3)c(=O)c2c1

InChI Key InChIKey=YQKBOUPIOWUMTE-NRFANRHFSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535742   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50535742(CHEMBL4592659)
Affinity DataEC50:  5.40nMAssay Description:Antagonist activity at integrin alpha4beta1 expressed in human Jurkat cells assessed as reduction in cell adhesion to human VCAM-1 incubated for 40 t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50535742(CHEMBL4592659)
Affinity DataEC50:  1.40nMAssay Description:Antagonist activity at integrin alpha4beta7 expressed in human RPMI8866 cells assessed as reduction in cell adhesion to rat MadCAM incubated for 40 t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed