BDBM50539556 CHEMBL4640695

SMILES CCn1nnc2c(C)c(ccc12)[C@@H](CC(O)=O)c1ccc2CCN(Cc2c1)C(=O)c1c(F)cccc1F

InChI Key InChIKey=INBSRKBKSGIXCC-NRFANRHFSA-N

Data  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50539556   

TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50539556(CHEMBL4640695)
Affinity DataEC50:  2.39E+3nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50539556(CHEMBL4640695)
Affinity DataKd:  21nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed