BDBM50542087 CHEMBL4635493::US11672785, Goodacre Compound 107

SMILES CCCN1CC(C1)Oc1cc(F)c([C@H]2N(CC(C)(C)F)[C@H](C)Cc3c2[nH]c2ccccc32)c(F)c1

InChI Key InChIKey=VJYIQQTZNGFHGR-XGCWNURASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50542087   

TargetEstrogen receptor(Homo sapiens (Human))
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50542087(CHEMBL4635493 | US11672785, Goodacre Compound 107)
Affinity DataIC50:  2.82nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50542087(CHEMBL4635493 | US11672785, Goodacre Compound 107)
Affinity DataIC50:  0.0650nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst staining based immunofluorescence imaging analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed