BDBM50544228 CHEMBL4647164
SMILES CN1CC(C1)C(=O)N[C@@H](CCCCCC(=O)c1ccon1)c1nnc(o1)-c1ccccc1F
InChI Key InChIKey=JMODMXNTOJTCLH-IBGZPJMESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50544228
Affinity DataIC50: 51nMAssay Description:Inhibition of full length human recombinant FLAG-tagged HDAC1 expressed in HEK293F cells using FLUOR DE LYS as substrate preincubated for 3 hrs follo...More data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Inhibition of full length human recombinant FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 cells using FLUOR DE LYS as substrate preincubate...More data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+3nMAssay Description:Inhibition of class 1 HDAC in human Jurkat model of HIV latency assessed as reactivation of HIV latency incubated for 20 hrs in presence of 5% NHS by...More data for this Ligand-Target Pair
Affinity DataIC50: >900nMAssay Description:Inhibition of HDAC6 (unknown origin) using FLUOR DE LYS as substrate preincubated for 3 hrs followed by substrate addition and measured after 60 mins...More data for this Ligand-Target Pair
Affinity DataIC50: >900nMAssay Description:Inhibition of human recombinant HDAC8 expressed in Escherichia coli using FLUOR DE LYS as substrate preincubated for 3 hrs followed by substrate addi...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s...More data for this Ligand-Target Pair