BDBM50545129 CHEMBL4645607

SMILES COc1cc(CN(C)C(=O)c2c(OCCCC3CCN(CC3)C(=O)OC3(C)CC3)c3cccnc3n(C)c2=O)cc(c1)C(F)(F)F

InChI Key InChIKey=MQJSYTCXEOBCLQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50545129   

TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545129(CHEMBL4645607)
Affinity DataIC50:  45nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545129(CHEMBL4645607)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50545129(CHEMBL4645607)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of mouse recombinant C-terminal FLAG-tagged SMS2 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed