BDBM50545140 CHEMBL4644666::US11591301, Compound 3
SMILES CCNS(=O)(=O)CCNc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O
InChI Key InChIKey=OPLHEFUSERQLPR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50545140
Affinity DataIC50: 95nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated for 60 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:IDO1 (His-tag) enzyme(BPS Bioscience), L-tryptophan (Sigma), methylene blue (Sigma), Catalase originated from the liver of cattle (Sigma), L-ascorbic...More data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated f...More data for this Ligand-Target Pair