BDBM50547205 CHEMBL4780750
SMILES [#6]-[#6][Si;v4]([#6]-[#6])([#6]-[#6])C#C[#6](=O)-[#7](-[#6](-[#6](=O)-[#7]-[#6]-[#6]-c1ccccc1)-c1cccs1)-c1ccc(-[#8]-[#6])c(Cl)c1
InChI Key InChIKey=GEVDAHDMRKQNIT-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50547205
TargetPhospholipid hydroperoxide glutathione peroxidase(Homo sapiens)
Institute Of Mit And Harvard
Curated by ChEMBL
Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataEC50: >3.30E+4nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1More data for this Ligand-Target Pair
TargetPhospholipid hydroperoxide glutathione peroxidase(Homo sapiens)
Institute Of Mit And Harvard
Curated by ChEMBL
Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataEC50: 370nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair