BDBM50547215 CHEMBL4758630

SMILES C\C=C(/C#N)C(=O)N1CCN(CC1)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=DMVGRADEFWHFMB-APQPDGGLSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547215   

TargetPhospholipid hydroperoxide glutathione peroxidase(Homo sapiens)
Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50547215(CHEMBL4758630)
Affinity DataEC50:  2.40E+4nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Homo sapiens)
Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50547215(CHEMBL4758630)
Affinity DataEC50:  2.20E+4nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed