BDBM50547764 CHEMBL4740457
SMILES O=C(N1CCCC(C1)c1ccnc2ncnn12)c1ccc2occc2c1
InChI Key InChIKey=HNDPBXHAFBXLSC-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50547764
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3B expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Janssen Pharmaceutica N. V.
Curated by ChEMBL
Affinity DataIC50: 447nMAssay Description:Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair