BDBM50548470 CHEMBL4749974

SMILES Fc1ccc(cc1)S(=O)(=O)N1C(C2CC2)C2(CCS(=N)(=O)CC2)c2cc(NC(=O)c3cccnc3)ccc12

InChI Key InChIKey=JTLIUTFVVQLNNM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50548470   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50548470(CHEMBL4749974)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human GnRH receptor expressed in CHO-K1 cells assessed as inhibition of LHRH-induced response preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50548470(CHEMBL4749974)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human GnRH receptor expressed in CHO-K1 cells assessed as inhibition of buserelin-induced response preincubated for 20 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50548470(CHEMBL4749974)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human GnRH receptor expressed in CHO-K1 cells assessed as inhibition of buserelin-induced response preincubated for 20 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50548470(CHEMBL4749974)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human GnRH receptor expressed in CHO-K1 cells assessed as inhibition of LHRH-induced response preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed