BDBM50548475 CHEMBL4747248

SMILES CC(=O)N1CCC2(CC1)C(C1CC1)N(c1ccc(NC(=O)c3cccc(F)c3)cc21)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=SNLRHKYGBNIMNQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548475   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50548475(CHEMBL4747248)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at human GnRH receptor expressed in CHO-K1 cells assessed as inhibition of buserelin-induced response preincubated for 20 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50548475(CHEMBL4747248)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human GnRH receptor expressed in CHO-K1 cells assessed as inhibition of LHRH-induced response preincubated for 20 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed