BDBM50553488 CHEMBL4743691
SMILES COc1cc(F)ccc1-c1ncnc(Nc2cccc(CS(N)(=O)=O)c2)n1
InChI Key InChIKey=MGCPJSMHKDVTGW-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50553488
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant full length His-tagged human CDK9/cyclin T1 expressed in baculovirus expression system using biotinylated peptide biotin-Tt...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Endotherm
Curated by ChEMBL
Endotherm
Curated by ChEMBL
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of recombinant GST-tagged human CDK2/GST-tagged cyclin E expressed in sf9 cells using biotinylated peptide biotin-Ttds-YISPLKSPYKISEG as s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+3nMAssay Description:Effective concentration required for inhibitory activity towards human beta-1 adrenergic receptorMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Endotherm
Curated by ChEMBL
Endotherm
Curated by ChEMBL
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of His-tagged human CDK2/cyclin E1 expressed in insect cells using biotin Ttds-YISPLKSPYKISEG as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Effective concentration required for inhibitory activity towards human beta-1 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of His-tagged human CDK9/cyclin T1 expressed in insect cells using biotin Ttds-YISPLKSPYKISEG as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair