BDBM50553499 CHEMBL4754493

SMILES Cn1ncc(c1CC1CC1)-c1nc(N[C@H]2CC[C@H](N)CC2)ncc1Cl

InChI Key InChIKey=RVZJFCNYSSUDCU-JOCQHMNTSA-N

Data  7 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50553499   

TargetCyclin-dependent kinase 7(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to wild-type human full length CDK7 (M1 to L344 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataKd:  4nMAssay Description:Binding affinity to wild-type human full length CDK9 (M1 to F372 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50:  4nMAssay Description:Inhibition of CDK9/Cyclin T (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50:  1.30nMAssay Description:Ability to displace [3H]glycine from strychnine-insensitive glycine receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of CSNK1D (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of CSNK1E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50:  4nMAssay Description:Ability to displace [3H]glycine from strychnine-insensitive glycine receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of CSNK1A1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed