BDBM50553499 CHEMBL4754493
SMILES Cn1ncc(c1CC1CC1)-c1nc(N[C@H]2CC[C@H](N)CC2)ncc1Cl
InChI Key InChIKey=RVZJFCNYSSUDCU-JOCQHMNTSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50553499
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKd: 1.30nMAssay Description:Binding affinity to wild-type human full length CDK7 (M1 to L344 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKd: 4nMAssay Description:Binding affinity to wild-type human full length CDK9 (M1 to F372 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK9/Cyclin T (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Ability to displace [3H]glycine from strychnine-insensitive glycine receptorMore data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of CSNK1D (unknown origin)More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of CSNK1E (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Ability to displace [3H]glycine from strychnine-insensitive glycine receptorMore data for this Ligand-Target Pair
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of CSNK1A1 (unknown origin)More data for this Ligand-Target Pair