BDBM50554389 CHEMBL4796570

SMILES C[C@H](NC(=O)[C@H](CCC(=O)NC(C)(C)C)NC(=O)c1cc(C)on1)C(=O)NCc1ccc(F)c2ccccc12

InChI Key InChIKey=LWLBWDRBVUDASR-JTSKRJEESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50554389   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50554389(CHEMBL4796570)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50554389(CHEMBL4796570)
Affinity DataIC50:  4.31E+3nMAssay Description:Inhibition of human 20S constitutive proteasome beta 5 chymotrypsin-like activity in human HeLa cells incubated for 2 hrs by proteasome-Glo assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50554389(CHEMBL4796570)
Affinity DataIC50:  53nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activity in human KARPAS-1106P cells incubated for 2 hrs by proteasome-Glo assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50554389(CHEMBL4796570)
Affinity DataIC50:  610nMAssay Description:Inhibition of human constitutive 20S proteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed