BDBM50556043 CHEMBL4740873
SMILES CN=[S@@]1(=O)C[C@](C)(N=C(N)N1CC(F)(F)F)c1cc(NC(=O)c2ncc(cc2C)C#N)ccc1F
InChI Key InChIKey=IGELCVKXEKUAED-NVXHTHCOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50556043
Affinity DataIC50: 0.590nMAssay Description:Inhibition of BACE1 in HEK293 cells harboring APP assessed as reduction in amyloidbeta 40 level measured after 18 to 20 hrs by AlphaLISA AssayMore data for this Ligand-Target Pair