BDBM50556452 CHEMBL4763420

SMILES Nc1ccccc1NC(=O)c1ccc(NC(=O)CCCCNc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)cc1

InChI Key InChIKey=CDVJLYDZKYPQJI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50556452   

TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50556452(CHEMBL4763420)
Affinity DataIC50:  420nMAssay Description:Inhibition of recombinant human C-terminal His/FLAG-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using Boc-Lys(epsilon-Ac)-AMC as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50556452(CHEMBL4763420)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50556452(CHEMBL4763420)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant human full-length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-Ac)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed