BDBM50557848 CHEMBL4777764::WO2021067859, Compound I-21

SMILES CC(C)(Nc1ncc(cc1F)C(=O)NO)c1ccccn1

InChI Key InChIKey=VYUAEMZSZDMXCF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50557848   

TargetHistone deacetylase 6(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50557848(CHEMBL4777764 | WO2021067859, Compound I-21)
Affinity DataIC50:  0.601nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using luminescent substrate by HDAC-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50557848(CHEMBL4777764 | WO2021067859, Compound I-21)
Affinity DataIC50:  0.601nMAssay Description:Table 14: The compounds disclosed herein, in particular those of Formula (II), were synthesized according to methods disclosed in WO2021067859, which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50557848(CHEMBL4777764 | WO2021067859, Compound I-21)
Affinity DataIC50:  0.639nMAssay Description:Table 14: The compounds disclosed herein, in particular those of Formula (II), were synthesized according to methods disclosed in WO2021067859, which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent