BDBM50557930 CHEMBL4740028

SMILES O=C(Nc1ccc(cc1N1CCOCC1)N1CCOCC1)c1cnn(n1)-c1ccccc1

InChI Key InChIKey=FIGVRMOGMRMIGE-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50557930   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human TRKA at active state by kinetic based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataKi:  1nMAssay Description:Inhibition of human TRKA at inactive state by kinetic based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataIC50:  1.59E+4nMAssay Description:Inhibition of human TRKB by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataIC50:  45nMAssay Description:Inhibition of human TRKA at active state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataIC50:  170nMAssay Description:Inhibition of human TRKA by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human TRKA kinase domain by HTRF KinEASE biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataIC50:  21nMAssay Description:Inhibition of human TRKA at inactive state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed