BDBM50558065 CHEMBL4780530
SMILES C[C@@H]1CN(c2ccc(Cl)cc2)c2cc(ccc2-n2c(C)nnc12)-c1ccc(N)nc1
InChI Key InChIKey=SBRJLPKKZHHGCO-CQSZACIVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50558065
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of His/FLAG-tagged BRD4 BD1 (unknown origin) using histone H4-TetraAcetylated-biotin peptide as substrate incubated for 20 mins by AlphaLI...More data for this Ligand-Target Pair
3D Structure (crystal)TargetBromodomain-containing protein 1(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of BRD1 (unknown origin) measured after 70 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of BRPF1 (unknown origin) measured after 70 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of BRD2 BD1 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of BRD2 BD2 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of BRD3 BD1 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of BRD3 BD2 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of BRDT BD1 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of BRDT BD2 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of His-tagged ATAD2 (unknown origin) using biotinylated acetylated peptide as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 9(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of His-tagged BRD9 (unknown origin) using biotinylated acetylated peptide as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
TargetBromodomain and PHD finger-containing protein 3(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of BRPF3 (unknown origin) measured after 70 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetTranscription activator BRG1(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of His-tagged BRG1 (unknown origin) using biotinylated acetylated peptide as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Constellation Pharmaceuticals
Curated by ChEMBL
Constellation Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of BPTF (unknown origin) measured after 70 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of His-tagged CBP (unknown origin) using biotinylated acetylated peptide as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair